In 1975, after becoming heavily involved in the Tamil movement, he carried out the first major political murder by a Tamil militant group, assassinating the mayor of Jaffna, Alfred Duraiappah, by shooting him at point-blank range when he was about to enter the Hindu temple at Ponnaalai. The assassination was in response to the 1974 Tamil conference incident, for which the Tamil radicals had blamed Duraiappah, because he backed the then ruling Sri Lanka Freedom Party. He was also seen by Tamil militants as betraying the Tamil nationalist sentiments in the Jaffna Peninsula, by allying with the Sinhalese majority government.
Founding of the LTTEOn May 5, 1976, the TNT was renamed the Liberation Tigers of Tamil Eelam (LTTE), commonly known as the Tamil Tigers.[not in citation given]
Religion was not a major factor in his philosophy or ideology, but the LTTE was characterized as anti-Buddhist. Prabhakaran himself was a lapsed Methodist. The LTTE was also an organization that did not cite any material from religion or religious texts in any of its ideological documents and propaganda but were driven only by the idea of Sri Lankan Tamil nationalism. They focused on this single-minded approach and inspiration toward the attainment of an independent Tamil Eelam.
 Press conference at KillinochchiPrabhakaran's first and only major press conference was held in Killinochchi on April 10, 2002. It was reported that more than 200 journalists from the local and foreign media attended this event and they had to go through a 10-hour security screening before the event in which Anton Balasingham introduced the LTTE leader as the "President and Prime minister of Tamil Eelam."
A number of questions were asked about LTTE's commitment towards the erstwhile peace process and Prabhakaran and Dr. Anton Balasingham jointly answered the questions.
Answering a question from one of the reporters Prabhakaran said that he has instructed the LTTE cadres to kill him if he compromised on the goal of independent state.
Repeated questions of his involvement in the Rajiv Gandhi assassination were only answered in a sober note by both Balasingham and Prabhakaran. They called it a "tragic incident" ("Thunbiyal Chambavam", as quoted in Tamil) they requested the press "not to dig into an incident that happened 10 years ago."
During the interview he stated that the right condition has not risen to give up the demand of Tamil Eelam. He further mentioned that "There are three fundamentals. That is Tamil homeland, Tamil nationality and Tamil right to self-determination. These are the fundamental demands of the Tamil people. Once these demands are accepted or a political solution is put forward by recognising these three fundamentals and our people are satisfied with the solutions we will consider giving up the demand for Eelam." He further added that Tamil Eelam was not only the demand of the LTTE but also the demand of the Tamil people.
Prabhakaran also answered a number of questions in which he reaffirmed their commitment towards peace process, quoted "We are sincerely committed to the peace process. It is because we are sincerely committed to peace that we continued a four month cessation of hostilities" was also firm in de-proscription of the LTTE by Sri Lanka and India, "We want the government of India to lift the ban on the LTTE. We will raise the issue at the appropriate time."
Prabhakaran also insisted firmly that only de-proscription would bring forth an amenable solution to the ongoing peace process mediated by Norway: "We have informed the government, we have told the Norwegians that de-proscription is a necessary condition for the commencements of talks."
 Philosophy and ideology
Prabhakaran never developed a systematic philosophy, but did declare that his goal was 'Revolutionary socialism and the creation of an egalitarian society'. He joined the Tamil nationalist movement in his youth and quickly established himself as a strong willed militant leader by founding the LTTE. His rare interviews, his annual Tamil Eelam Heroes Day speeches and the policies and actions of the LTTE can be taken as indicators of Prabhakaran’s philosophy and ideology. The following are important areas when considering philosophy and ideology of Prabhakaran."Few dispute he was one of the most effective guerrilla leaders in modern warfare – displaying the tactical prowess of Afghanistan's Ahmad Shah Masoud, the ruthlessness of Osama bin Laden and the conviction of Latin American revolutionary Che Guevara."